The Castille Hotel is located in the heart of Valletta, within a few minutes walk from National Museum of Archaeology and Manoel Theatre. Valletta's attractions, such as National War Museum and Auberge de Castille are easily accessible on foot.

The Castille Hotel offers a convenient 24-hour reception as well as a concierge for its guests. The hotel also offers guests the added convenience of a Wi-Fi connection. Popular tourist spots are within easy walking distance from the hotel. Bisazza is within a 20 minute drive from the hotel.

The Castille Hotel is a five-minute walk from many attractions including National Museum of Fine Arts, Casa Rocca Piccola and Carmelite Church. Malta International Airport (MLA) is a 30 minute drive from the hotel. Triq Manwel Dimech is a five minute drive from the hotel.